Hoxc6^tm1Dds
Targeted Allele Detail

Summary

• Symbol: Hoxc6^tm1Dds
• Name: homeobox C6; targeted mutation 1, Demetri D Spyropoulos
• MGI ID: MGI:2150689
• Gene: Hoxc6 Location: Chr15:102906689-102920313 bp, + strand Genetic Position: Chr15, 58.06 cM, cytoband E2
• Alliance: Hoxc6^tm1Dds page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:64980
• Parent Cell Line: CC1.2 (ES Cell)
• Strain of Origin: 129S7/SvEvBrd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• Mutation details: Gene disruption was caused by insertion of a neomycin resistance cassette into genomic sequences that encode peptide regions upstream of the first helix of the homeodomain. (J:64980)

Expression

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hoxc6 Mutation: 11 strains or lines available

References

• Original: J:64980 Garcia-Gasca A, et al., Differential mammary morphogenesis along the anteroposterior axis in hoxc6 gene targeted mice. Dev Dyn. 2000 Oct;219(2):261-76
• All: 6 reference(s)