Lepr^db-dmpg
Spontaneous Allele Detail

Summary

• Symbol: Lepr^db-dmpg
• Name: leptin receptor; dumpling
• MGI ID: MGI:2151179
• Gene: Lepr Location: Chr4:101574601-101672549 bp, + strand Genetic Position: Chr4, 46.96 cM
• Alliance: Lepr^db-dmpg page

Mutation origin

• Strain of Origin: B10.D2-H8^b/Sn

Mutation description

• Allele Type: Spontaneous
• Mutation: Deletion
• Lepr^db-dmpg involves 1 genes/genome features (Lepr) View all
• Mutation details: This allele has a large genomic deletion which includes exons 2 through 6. The proximal deletion breakpoint has not yet been localized but the most closely flanking proximal microsatellite marker (D4Mit176) was not deleted. (J:83762)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Lepr Mutation: 122 strains or lines available

References

• Original: J:83762 Kim JH, et al., New leptin receptor mutations in mice: Lepr(db-rtnd), Lepr(db-dmpg) and Lepr(db-rlpy). J Nutr. 2003 May;133(5):1265-71
• All: 1 reference(s)