Hoxb6^tm1Mrc
Targeted Allele Detail

Summary

• Symbol: Hoxb6^tm1Mrc
• Name: homeobox B6; targeted mutation 1, Mario R Capecchi
• MGI ID: MGI:2151485
• Synonyms: hoxb-6^-
• Gene: Hoxb6 Location: Chr11:96183647-96192395 bp, + strand Genetic Position: Chr11, 59.82 cM
• Alliance: Hoxb6^tm1Mrc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:22424
• Parent Cell Line: CC1.2 (ES Cell)
• Strain of Origin: 129S7/SvEvBrd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• A neomycin cassette was inserted into the coding sequence of the first exon. (J:22424)

Expression

In Mice Carrying this Mutation:	4 assay results 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hoxb6 Mutation: 14 strains or lines available

References

• Original: J:22424 Rancourt DE, et al., Genetic interaction between hoxb-5 and hoxb-6 is revealed by nonallelic noncomplementation. Genes Dev. 1995 Jan 1;9(1):108-22
• All: 4 reference(s)