Hoxb2^tm1Fmr
Targeted Allele Detail

Summary

• Symbol: Hoxb2^tm1Fmr
• Name: homeobox B2; targeted mutation 1, Filippo M Rijli
• MGI ID: MGI:2151774
• Synonyms: Hoxb2^-
• Gene: Hoxb2 Location: Chr11:96242458-96244846 bp, + strand Genetic Position: Chr11, 59.85 cM
• Alliance: Hoxb2^tm1Fmr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:54652
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129/Sv

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A lacZ gene was inserted in frame into exon 1, replacing 300 bp of exonic/intronic sequence. A neomycin cassette was inserted following the lacZ gene. (J:54652)

Expression

In Mice Carrying this Mutation:	57 assay results
In Structures Affected by this Mutation:	2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hoxb2 Mutation: 12 strains or lines available

References

• Original: J:54652 Davenne M, et al., Hoxa2 and Hoxb2 control dorsoventral patterns of neuronal development in the rostral hindbrain. Neuron. 1999 Apr;22(4):677-91
• All: 2 reference(s)