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Msh3tm1Htr
Targeted Allele Detail
Summary
Symbol: Msh3tm1Htr
Name: mutS homolog 3; targeted mutation 1, Hein te Riele
MGI ID: MGI:2151802
Gene: Msh3  Location: Chr13:92348387-92491515 bp, - strand  Genetic Position: Chr13, 47.63 cM
Alliance: Msh3tm1Htr page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:59561
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
    Exon 2 was disrupted by insertion of a vector containing the hygromycin resistance gene. (J:59561)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Tumor Data
List all tumor models in MMHCdb carrying Msh3tm1Htr
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Msh3 Mutation:  61 strains or lines available
References
Original:  J:59561 de Wind N, et al., HNPCC-like cancer predisposition in mice through simultaneous loss of Msh3 and Msh6 mismatch-repair protein functions. Nat Genet. 1999 Nov;23(3):359-62
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory