Hoxa13^tm1Mrc
Targeted Allele Detail

Summary

• Symbol: Hoxa13^tm1Mrc
• Name: homeobox A13; targeted mutation 1, Mario R Capecchi
• MGI ID: MGI:2152348
• Synonyms: Hoxa13^GFPneo
• Gene: Hoxa13 Location: Chr6:52235833-52237865 bp, - strand Genetic Position: Chr6, 25.41 cM
• Alliance: Hoxa13^tm1Mrc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:72301
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: A cassette containing GFP and an adjacent floxed neomycin resistance cassette was inserted in-frame into exon 2. (J:72301)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hoxa13 Mutation: 29 strains or lines available

References

• Original: J:72301 Stadler HS, et al., Loss of Eph-receptor expression correlates with loss of cell adhesion and chondrogenic capacity in Hoxa13 mutant limbs. Development. 2001 Nov;128(21):4177-88
• All: 1 reference(s)