Esx1^tm1Bhr
Targeted Allele Detail

Summary

• Symbol: Esx1^tm1Bhr
• Name: extraembryonic, spermatogenesis, homeobox 1; targeted mutation 1, Richard R Behringer
• MGI ID: MGI:2153820
• Synonyms: X^Esx1
• Gene: Esx1 Location: ChrX:136016146-136022832 bp, - strand Genetic Position: ChrX, 59.1 cM
• Alliance: Esx1^tm1Bhr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:50590
• Parent Cell Line: AB1 (ES Cell)
• Strain of Origin: 129S7/SvEvBrd-Hprt1⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• A neomycin resistance cassette replaced 5.2 kb of sequence that contains all four coding exons. (J:50590)

Expression

In Structures Affected by this Mutation:

5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Esx1 Mutation: 1 strain or line available

References

• Original: J:50590 Li Y, et al., Esx1 is an X-chromosome-imprinted regulator of placental development and fetal growth. Nat Genet. 1998 Nov;20(3):309-11
• All: 1 reference(s)