Gcm1^tm1Weg
Targeted Allele Detail

Summary

• Symbol: Gcm1^tm1Weg
• Name: glial cells missing homolog 1; targeted mutation 1, Michael Wegner
• MGI ID: MGI:2153827
• Synonyms: mGCMa -
• Gene: Gcm1 Location: Chr9:77959240-77972906 bp, + strand Genetic Position: Chr9, 43.49 cM, cytoband E1-E3
• Alliance: Gcm1^tm1Weg page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:61094
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• In-frame insertion of a lacZ-neomycin resistance cassette replaced exon 3 to 6. (J:61094)

Expression

In Mice Carrying this Mutation:

28 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gcm1 Mutation: 23 strains or lines available

References

• Original: J:61094 Schreiber J, et al., Placental failure in mice lacking the mammalian homolog of glial cells missing, GCMa. Mol Cell Biol. 2000 Apr;20(7):2466-74
• All: 3 reference(s)