Summary |
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Variant origin |
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Variant description |
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Phenotypes |
View phenotypes and curated references for all genotypes (concatenated display).
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Expression |
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Notes |
Significant interaction between Ccrs1 and Ccrs2 has been detected.
Mapping and Phenotype information for this QTL, its variants and associated markersJ:5105265 loci with an average spacing approximately of 25 cM were screened in 284 (C57BL/6By x NZB/B1NJ)F2 animals for linkage with corpus callosum hemisphere surface size. NZB/B1NJ has smaller corpus callosum hemisphere surface size compared to C57BL/6By. QTLs affecting corpus callosum hemisphere surface size, Ccrs1 and Ccrs2, were identified on mouse Chromosome 1 and mouse Chromosome 4, respectively. Ccrs1 maps to 81.6 cM - 106.3 cM on Chromosome 1 with a peak LOD score of 4.23 at D1Mit14. Ccrs2 maps to 57.6 cM - 78.5 cM on Chromosome 4 with a peak LOD score of 2.72 at D4Mit12. Two-way analyses showed significant interaction between Ccrs1 and Ccrs2. |
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References |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/12/2024 MGI 6.24 |
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