Orch4^DBA/2J
QTL Variant Detail

Summary

• QTL variant: Orch4^DBA/2J
• Name: autoimmune orchitis resistance 4; DBA/2J
• MGI ID: MGI:2154295
• QTL: Orch4 Location: Chr1:192211318-192211423 bp Genetic Position: Chr1, cM position of peak correlated region/allele: 97.55 cM
• QTL Note: genome coordinates based on the marker associated with the peak LOD score

Variant origin

• Strain of Specimen: DBA/2J

Variant description

• Allele Type: QTL
• Mutation: Undefined
• This allele confers orchitis resistance compared to BALB/cByJ. (J:35331)
• Inheritance: Dominant

References

• Original: J:35331 Meeker ND, et al., Multiple loci govern the bone marrow-derived immunoregulatory mechanism controlling dominant resistance to autoimmune orchitis. Proc Natl Acad Sci U S A. 1995 Jun 6;92(12):5684-8
• All: 1 reference(s)