Gsx1^tm1Ssp
Targeted Allele Detail

Summary

• Symbol: Gsx1^tm1Ssp
• Name: GS homeobox 1; targeted mutation 1, S Steven Potter
• MGI ID: MGI:2154448
• Gene: Gsx1 Location: Chr5:147125506-147127757 bp, + strand Genetic Position: Chr5, 86.79 cM
• Alliance: Gsx1^tm1Ssp page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:31764
• Parent Cell Line: E14TG2a (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A PGK-HPRT resistance cassette replaced a large part of the first exon, the entire intron and the entire second exon including the sequences encoding the homeobox. (J:31764)

Expression

In Mice Carrying this Mutation:	25 assay results
In Structures Affected by this Mutation:	9 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gsx1 Mutation: 11 strains or lines available

References

• Original: J:31764 Li H, et al., Gsh-1, an orphan Hox gene, is required for normal pituitary development. EMBO J. 1996 Feb 15;15(4):714-24
• All: 13 reference(s)