Smarcc1^tm1Rhs
Targeted Allele Detail

Summary

• Symbol: Smarcc1^tm1Rhs
• Name: SWI/SNF related BAF chromatin remodeling complex subunit C1; targeted mutation 1, Rho H Seong
• MGI ID: MGI:2154523
• Synonyms: Srg3-
• Gene: Smarcc1 Location: Chr9:109961129-110069773 bp, + strand Genetic Position: Chr9, 59.87 cM
• Alliance: Smarcc1^tm1Rhs page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:72635
• Parent Cell Line: AK7 (ES Cell)
• Strain of Origin: 129S4/SvJaeSor

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A PGK-neomycin resistance cassette replaced exon 4, which encodes amino acid residues 131-158, and placed exon 5 out of frame with exon 3. (J:72635)

Expression

In Mice Carrying this Mutation:	6 assay results
In Structures Affected by this Mutation:	9 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Smarcc1 Mutation: 69 strains or lines available

References

• Original: J:72635 Kim JK, et al., Srg3, a mouse homolog of yeast swi3, is essential for early embryogenesis and involved in brain development. Mol Cell Biol. 2001 Nov;21(22):7787-95
• All: 3 reference(s)