Del(6Snca)1Slab
Spontaneous Allele Detail

Summary

• Symbol: Del(6Snca)1Slab
• Name: deletion, Chr 6, Schoepfer Lab 1
• MGI ID: MGI:2154692
• Synonyms: alphaS^-, alpha-syn^-, C57BL/6S, Del1Slab, Del(6)Snca1Slab
• Gene: Del(6Snca)1Slab Location: unknown Genetic Position: Chr6, Syntenic

Mutation origin

• Strain of Origin: C57BL/6JOlaHsd

Mutation description

• Allele Type: Spontaneous
• Mutation: Intergenic deletion
• Del(6Snca)1Slab involves 3 genes/genome features (Snca, Gm43864, Mmrn1) View all
• Mutation details: This chromosomal deletion is 365 kb in length and includes both the Snca gene and the Mmrn1 gene, but not Atoh1 or Atoh2. The deletion was not present in C57BL/6J DNA provided from the Jackson Laboratory, in contrast to C57BL/6JOlaHsd mice from Harlan. (J:90239, J:125212)

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Del(6Snca)1Slab Mutation: 1 strain or line available

References

• Original: J:72488 Specht CG, et al., Deletion of the alpha-synuclein locus in a subpopulation of C57BL/6J inbred mice. BMC Neurosci. 2001;2(1):11
• All: 39 reference(s)