Bgeq2^SM/J
QTL Variant Detail

Summary

• QTL variant: Bgeq2^SM/J
• Name: body growth early QTL 2; SM/J
• MGI ID: MGI:2154961
• QTL: Bgeq2 Location: unknown Genetic Position: Chr2, Syntenic

Variant origin

• Strain of Specimen: SM/J

Variant description

• Allele Type: QTL
• Mutation: Undefined
• This allele confers increased early growth rate compared to LG/J. (J:32208)
• Inheritance: Not Specified

Notes

Mapping and Phenotype information for this QTL, its variants and associated markers

J:32208

Quantitative trait loci (QTLs) effecting age specific body growth rates in mice were mapped using 535 F2 intercross mice from a (LG/J x SM/J)F1 cross. LG/J mice exhibit a large size at 60 days of age whereas SM/J exhibit a Small size. QTLs on 16 of 19 autosomes effective age specific growth was detected in a genome wide scan using microsatellite markers. QTL marker Bglq2 was associated with late growth rate and mapped to mouse Chromosome 2 near D2Mit22. A QTL marker Bgeq2 was associated with early growthnear D2Mit17.

J:60662

Quantitative trait loci (QTLs) effecting age specific body growth rates in mice were mapped in a previous experiment using 535 F2 intercross mice from a (LG/J x SM/J)F1 cross (See J:32208). Here an additional 510 F2 mice were analysed. LG/J mice exhibit a large size at 60 days of age whereas SM/J exhibit a Small size. QTL markers Bgeq2 and Bglq2 were reaffirmed as mapping to mouse Chromosome 2.

References

• Original: J:60662 Vaughn TT, et al., Mapping quantitative trait loci for murine growth: a closer look at genetic architecture. Genet Res. 1999 Dec;74(3):313-22
• All: 2 reference(s)