Alcp5^C57BL/6J
QTL Variant Detail

Summary

• QTL variant: Alcp5^C57BL/6J
• Name: alcohol preference locus 5, male specific; C57BL/6J
• MGI ID: MGI:2155056
• QTL: Alcp5 Location: Chr2:180486407-180486559 bp Genetic Position: Chr2, cM position of peak correlated region/allele: 103.43 cM
• QTL Note: genome coordinates based on the marker associated with the peak LOD score

Variant origin

• Strain of Specimen: C57BL/6J

Variant description

• Allele Type: QTL
• Inheritance: Not Specified

Notes

Mapping and Phenotype information for this QTL, its variants and associated markers

J:52467

Alcohol consumption and preference in mice were analyzed as a QTL in Recombinant Inbreds(RI) AXB and BXA and progenitor inbreds C57BL/6J and A/J. In males QTLs were found on mouse Chromosomes 2, 5, 7, 10, 11 and 16, and in females QTLs were found on Chromosomes 2, 4, 5, 7, 11, 16, and 19. A QTL for alcohol preference in male AXB/BXA mice was associated with marker D2Mit74 with a LOD score of 3.5 and is designated as Alcp5. Alcp5 did not overlap with Alcp1 as published in J:33277 Melo JA, Nat Genet 1996 Jun;13(2):147-53. In addition A QTL for alcohol preference in female AXB/BXA mice was also associated with marker D2Mit74 with a LOD score of 2.15 and is designated as Alcp6.

References

• Original: J:52467 Gill K, et al., Alcohol preference in AXB/BXA recombinant inbred mice: gender differences and gender-specific quantitative trait loci. Mamm Genome. 1998 Dec;9(12):929-35
• All: 1 reference(s)