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EtohilaC57BL/6J
QTL Variant Detail
Summary
QTL variant: EtohilaC57BL/6J
Name: ethanol induced locomotor activity; C57BL/6J
MGI ID: MGI:2155095
QTL: Etohila  Location: Chr2:80005954-80006113 bp  Genetic Position: Chr2, cM position of peak correlated region/allele: 47.93 cM
QTL Note: genome coordinates based on the marker associated with the peak LOD score
Variant
origin
Strain of Specimen:  C57BL/6J
Variant
description
Allele Type:    QTL
Inheritance:    Other (see notes)
Notes
Etohila exhibits an additive mode of inheritance.

Mapping and Phenotype information for this QTL, its variants and associated markers

J:52087

In a genome wide scan of 925 (C57BL/6J x DBA/2J)F2 mice an ethonal-induced activation Quatatative Trait Locus(QTL) was associated with a region on mouse Chromosome 2. A LOD score of 8.4 was found at cM 52 and was associated with marker D2Mit94. The 1-LOD support interval spans 17 cM. This locus accounts for 11.4% of the phenotypic variance. Suggestive QTLs were also found at D1Mit22, D5Mit371, and D6Mit371.

References
Original:  J:52087 Hitzemann R, et al., Genetics of ethanol-induced locomotor activation: detection of QTLs in a C57BL/6J x DBA/2J F2 intercross. Mamm Genome. 1998 Dec;9(12):956-62
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/05/2024
MGI 6.24
The Jackson Laboratory