Bwfq1^CAST/EiJ
QTL Variant Detail

Summary

• QTL variant: Bwfq1^CAST/EiJ
• Name: body weight and fat QTL 1; CAST/EiJ
• MGI ID: MGI:2155195
• QTL: Bwfq1 Location: unknown Genetic Position: Chr2, Syntenic

Variant origin

• Strain of Specimen: CAST/EiJ

Variant description

• Allele Type: QTL
• Inheritance: Not Specified

Notes

Mapping and Phenotype information for this QTL, its variants and associated markers

J:35301

Genome scan was performed on 421 animals from a M16i x (M16i x CAST/Ei)F1 backcross population to identify QTLs associated with body fat and body weight. Parental strain M16i displays rapid weight gain and increased body weight and fat carcasses, whereasparental strain CAST/Ei displays low body weight and lean carcasses. Significant linkage was detected on mouse Chromosome 2 at 56 cM - 65 cM (Bwfq1, LOD = 6.1 for association to body weight and LOD = 4.1 for association to gonadal fat pad weight) and at 77 cM - 90 cM (Bwfq2, LOD = 3.5 for association to body weight and LOD = 4.3 for association to gonadal fat pad weight). Bwfq2 maps near potential candidate genes agouti (a) and growth hormone releasing hormone (Ghrh).

References

• Original: J:35301 Drudik DK, et al., Identification of major genes controlling body weight and fat percentage on mouse Chromosome 2. J Anim Sci. 1995;73(Suppl 1):110 (Abstr.)
• All: 1 reference(s)