Hrh3^Eae8-r
Allele Detail

Summary

• Symbol: Hrh3^Eae8-r
• Name: histamine receptor H3; experimental allergic encephalomyelitis susceptibility 8, resistant
• MGI ID: MGI:2155218
• Synonyms: Hrh3^Eae8-B10.S
• Gene: Hrh3 Location: Chr2:179741258-179746264 bp, - strand Genetic Position: Chr2, 102.62 cM
• Alliance: Hrh3^Eae8-r page

Mutation origin

• Strain of Origin: multiple strains

Mutation description

• Allele Type: Not Applicable
• Mutation: Undefined
• Mutation details: Strains 129/Sv, A/J, AKR/J, B10.S/DvTe, BALB/cJ, BALB/cByJ, C57BL/6J, CBA/J, DBA/1J, FVB/NJ, NOD/LtJ, NZB/BInJ and PL/J contain a glycine at position 293 compared with the amino acid aspartic acid at position 293 in strains C3H/HeJ, DBA/2J, NZW/LacJ, P/J and SJL. This allele confers EAE resistance compared to SJL/J. (J:34892)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hrh3 Mutation: 20 strains or lines available

References

• Original: J:34892 Encinas JA, et al., Genetic analysis of susceptibility to experimental autoimmune encephalomyelitis in a cross between SJL/J and B10.S mice. J Immunol. 1996 Sep 1;157(5):2186-92
• All: 2 reference(s)