Summary |
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Variant origin |
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Variant description |
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Phenotypes |
View phenotypes and curated references for all genotypes (concatenated display).
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Expression |
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Notes |
Afw12 exhibits an additive mode of inheritance.
Trait Annotation
Mapping and Phenotype information for this QTL, its variants and associated markersJ:66233QTL effecting body weight, obesity and muscle weight were found on mouse Chromosomes 1, 4, 5, 7, 11, 12, 13, and 17 and for leptin on 14 and insulin on chromosome 4. The cross used in the genome wide scan included approximately 400 F2 mice from a (DU6i xDBA/2)F1 intercross. DU6i is a strain selected for high body weight. 93 microsatellite markers were analyzed in the genome wide scan. Locations of the QTL were provided by the authors and may not be equivalent to the closest microsatellites. Abdominal fat percent QTL 1 was mapped to mouse Chromosome 3 with a cM range from 23 to 37 cM. Abdominal fat weight QTL was mapped to mouse Chromosome 3 position 30 with a range from 23 to 36 cM. 10.03.2014 - Curator Note: We had originally associated the abdominal fat weight QTL identified here, mapping to 30 cM between 23 and 36cM on mouse Chr 3, as Afw1. Afw1 was originally mapped using a different cross, an outbred cross of DU6 x DUK, in J:49578 in 1998. We consider the current mapping study a separate mapping experiment and have named the QTL identified here as Afw12.04.14.2015 - Curator Note: The abdominal fat percent QTL 1 (Afpq1) was originally mapped in J:49578 in 1998 using DU6 (selected for high body weight) and a DUKs female mice, which differ from the cross used here. We consider the current mapping study a separate mapping experiment and have named the QTL identified here mapping to mouse Chromosome 3 with a cM range from 23 to 37 cM as Apfq7. |
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References |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 10/29/2024 MGI 6.24 |
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