Tyrp1^b-1ETOPc
Chemically induced Allele Detail

Summary

• Symbol: Tyrp1^b-1ETOPc
• Name: tyrosinase-related protein 1; brown 1ETOPc
• MGI ID: MGI:2155307
• Synonyms: b^1ETOPc
• Gene: Tyrp1 Location: Chr4:80752360-80769956 bp, + strand Genetic Position: Chr4, 37.89 cM
• Alliance: Tyrp1^b-1ETOPc page

Mutation origin

• Strain of Origin: (101/Rl x C3H/Rl)F1

Mutation description

• Allele Type: Chemically induced (other)
• Mutation: Intergenic deletion
• Large intergenic deletion. (J:73422)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Tyrp1 Mutation: 162 strains or lines available

Notes

The chemical mutagen used was etoposide.

References

• Original: J:73422 Russell LB, et al., Unlike other chemicals, etoposide (a topoisomerase-II inhibitor) produces peak mutagenicity in primary spermatocytes of the mouse. Mutat Res. 1998 May 25;400(1-2):279-86
• All: 2 reference(s)