Scc7^STS/A
QTL Variant Detail

Summary

• QTL variant: Scc7^STS/A
• Name: colon tumor susceptibility 7; STS/A
• MGI ID: MGI:2155331
• QTL: Scc7 Location: Chr3:143352986-156364108 bp Genetic Position: Chr3, cM position of peak correlated region/allele: 72.36 cM
• QTL Note: genome coordinates based on the marker associated with the peak LOD score

Variant origin

• Strain of Specimen: STS/A

Variant description

• Allele Type: QTL
• Mutation: Undefined
• Mutation details: The effect of this allele depends upon the genotype at Scc8. STS/A-derived alleles at Scc7 and Scc8 confers susceptibility to colon tumors. (J:57235)
• Inheritance: Other (see notes)

Notes

Scc7 participates in interactive effects with Scc8. STS/A-derived alleles at Scc7 and Scc8 confers tumor susceptibility.

References

• Original: J:57235 van Wezel T, et al., Four new colon cancer susceptibility loci, Scc6 to Scc9 in the mouse. Cancer Res. 1999 Sep 1;59(17):4216-8
• All: 1 reference(s)