Bh4p^C57BL/6By
QTL Variant Detail

Summary

• QTL variant: Bh4p^C57BL/6By
• Name: bar holding four paws; C57BL/6By
• MGI ID: MGI:2155362
• QTL: Bh4p Location: Chr3:48837854-48837997 bp Genetic Position: Chr3, cM position of peak correlated region/allele: 21.67 cM
• QTL Note: genome coordinates based on the marker associated with the peak LOD score

Variant origin

• Strain of Specimen: C57BL/6By

Variant description

• Allele Type: QTL
• Mutation: Undefined
• This allele confers earlier ability to hold onto a bar with four paws compared to NZB/BlNJ. (J:53794)
• Inheritance: Dominant

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Notes

Mapping and Phenotype information for this QTL, its variants and associated markers

J:53794

Nineteen measures of sensorial, motor and body weight were subject to analysis in 389 female and male mice derived from reciprocal F1 and F2 mating of strains C57BL6/By and NZB/BlNJ . These traits were mapped via QTL analysis. In total 36 traits were mapped to chromosomes of which a number reached a threshold LOD score of 3.13 and were thus concidered significant. One such QTL, bar holding four paws (Bh4p) mapped with mouse Chromosome 3 marker D3Mit6 with a LOD score of 3.20. The C57BL/6By-derived allele confers earlier ability to hold onto a bar with four paws (day 10.66) and is inherited dominantly.

References

• Original: J:53794 Le Roy I, et al., Preweanling sensorial and motor development in laboratory mice: quantitative trait loci mapping. Dev Psychobiol. 1999 Mar;34(2):139-58
• All: 1 reference(s)