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Bh4pNZB/BlNJ
QTL Variant Detail
Summary
QTL variant: Bh4pNZB/BlNJ
Name: bar holding four paws; NZB/BlNJ
MGI ID: MGI:2155363
QTL: Bh4p  Location: Chr3:48837854-48837997 bp  Genetic Position: Chr3, cM position of peak correlated region/allele: 21.67 cM
QTL Note: genome coordinates based on the marker associated with the peak LOD score
Variant
origin
Strain of Specimen:  NZB/BlNJ
Variant
description
Allele Type:    QTL
Inheritance:    Recessive
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Notes

Mapping and Phenotype information for this QTL, its variants and associated markers

J:53794

Nineteen measures of sensorial, motor and body weight were subject to analysis in 389 female and male mice derived from reciprocal F1 and F2 mating of strains C57BL6/By and NZB/BlNJ . These traits were mapped via QTL analysis. In total 36 traits were mapped to chromosomes of which a number reached a threshold LOD score of 3.13 and were thus concidered significant. One such QTL, bar holding four paws (Bh4p) mapped with mouse Chromosome 3 marker D3Mit6 with a LOD score of 3.20. The C57BL/6By-derived allele confers earlier ability to hold onto a bar with four paws (day 10.66) and is inherited dominantly.

References
Original:  J:53794 Le Roy I, et al., Preweanling sensorial and motor development in laboratory mice: quantitative trait loci mapping. Dev Psychobiol. 1999 Mar;34(2):139-58
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory