Dlx3^tm1Mso
Targeted Allele Detail

Summary

• Symbol: Dlx3^tm1Mso
• Name: distal-less homeobox 3; targeted mutation 1, Maria I Morasso
• MGI ID: MGI:2155443
• Gene: Dlx3 Location: Chr11:95010945-95016122 bp, + strand Genetic Position: Chr11, 59.01 cM
• Alliance: Dlx3^tm1Mso page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:52247
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• A neomycin cassette replaced much of the coding region of the gene. (J:52247)

Expression

In Mice Carrying this Mutation:	19 assay results
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dlx3 Mutation: 11 strains or lines available

References

• Original: J:52247 Morasso MI, et al., Placental failure in mice lacking the homeobox gene Dlx3. Proc Natl Acad Sci U S A. 1999 Jan 5;96(1):162-7
• All: 4 reference(s)