Pact1^SWR/Bm
QTL Variant Detail

Summary

• QTL variant: Pact1^SWR/Bm
• Name: platelet activation 1; SWR/Bm
• MGI ID: MGI:2155459
• QTL: Pact1 Location: unknown Genetic Position: Chr3, cM position of peak correlated region/allele: 29.17 cM
• QTL Note: genome coordinates based on the marker associated with the peak LOD score

Variant origin

• Strain of Specimen: SWR/Bm

Variant description

• Allele Type: QTL
• Inheritance: Not Specified

Notes

Mapping and Phenotype information for this QTL, its variants and associated markers

J:43555

Linkage analysis was performed on 14 SWXJ (SWR/Bm x SJL/Bm) recombinant inbred strains and 20 AKXD (AKR/J x DBA/2J) recombinant inbred strains to identify QTLs associated with platelet activation. Parental strains SJL/Bm and AKR/J exhibit high levels of spontaneous platelet activation compared to parental strains SWR/Bm and DBA/2J. Linkage to the platelet activation phenotype mapped to approximately 27 cM on mouse Chromosome 3 and is named Pact1 (platelet activation 1). Pact1 is linked to D3Mit7 in the SWXJ RI strains and is linked to D3Nds1 in the AKR/J RI strains.

References

• Original: J:43555 Ault KA, et al., Genetic control of platelet activation in inbred mouse strains. Platelets. 1997;8(4):235-241
• All: 1 reference(s)