Cd3e^tm1Cpt
Targeted Allele Detail

Summary

• Symbol: Cd3e^tm1Cpt
• Name: CD3 antigen, epsilon polypeptide; targeted mutation 1, Cox Terhorst
• MGI ID: MGI:2155671
• Synonyms: epsilon^deltaP
• Gene: Cd3e Location: Chr9:44910038-44920925 bp, - strand Genetic Position: Chr9, 24.84 cM
• Alliance: Cd3e^tm1Cpt page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:54756
• Parent Cell Line: J1 (ES Cell)
• Strain of Origin: 129S4/SvJae

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• A PGK-neomycin resistance cassette replaced the promoter region and exons 1, 2, and 3. (J:54756)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cd3e Mutation: 54 strains or lines available

References

• Original: J:54756 Wang N, et al., Expression of a CD3 epsilon transgene in CD3 epsilon(null) mice does not restore CD3 gamma and delta expression but efficiently rescues T cell development from a subpopulation of prothymocytes. Int Immunol. 1998 Dec;10(12):1777-88
• All: 11 reference(s)