Cacng2^stg-3J
Spontaneous Allele Detail

Summary

• Symbol: Cacng2^stg-3J
• Name: calcium channel, voltage-dependent, gamma subunit 2; stargazer 3 Jackson
• MGI ID: MGI:2155891
• Gene: Cacng2 Location: Chr15:77875948-78004228 bp, - strand Genetic Position: Chr15, 36.92 cM
• Alliance: Cacng2^stg-3J page

Mutation origin

• Strain of Origin: BALB/cJ

Mutation description

• Allele Type: Spontaneous
• Mutation: Transposon insertion
• Mutation details: The phenotype of the stargazer 3J mouse has been attributed to an early transposon (ETn) insertion into intron 2, approximately 2 kb downstream from the site of the ETn insertion that gave rise to the original stargazer mutation. RT-PCR analysis demonstrated that in addition to two aberrant transcripts generated by the insertion, some normally spliced mRNA was detected, suggesting that this mutation does not represent a complete null allele. (J:84624)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Cacng2 Mutation: 26 strains or lines available

References

• Original: J:84624 Letts VA, et al., Phenotypic heterogeneity in the stargazin allelic series. Mamm Genome. 2003 Aug;14(8):506-13
• All: 2 reference(s)