Cacna1a^tg-4J
Spontaneous Allele Detail

Summary

• Symbol: Cacna1a^tg-4J
• Name: calcium channel, voltage-dependent, P/Q type, alpha 1A subunit; tottering 4 Jackson
• MGI ID: MGI:2155892
• Gene: Cacna1a Location: Chr8:85065268-85366875 bp, + strand Genetic Position: Chr8, 40.95 cM
• Alliance: Cacna1a^tg-4J page

Mutation origin

• Strain of Origin: C3H/HeJBir

Mutation description

• Allele Type: Spontaneous
• Mutation: Single point mutation
• Mutation details: A T to C substitution at coding cDNA nucleotide 1886 (c.1886T>C) results in a change of valine codon 629 to alanine (p.V629A). (J:137816)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Cacna1a Mutation: 118 strains or lines available

References

• Original: J:137816 Miki T, et al., Two novel alleles of tottering with distinct Ca(v)2.1 calcium channel neuropathologies. Neuroscience. 2008 Jul 31;155(1):31-44
• All: 1 reference(s)