Fecq2^C57BL/6J
QTL Variant Detail

Summary

• QTL variant: Fecq2^C57BL/6J
• Name: fecundity QTL 2; C57BL/6J
• MGI ID: MGI:2155909
• QTL: Fecq2 Location: Chr4:117071971-117072206 bp Genetic Position: Chr4, cM position of peak correlated region/allele: 53.43 cM
• QTL Note: genome coordinates based on the marker associated with the peak LOD score

Variant origin

• Strain of Specimen: C57BL/6J

Variant description

• Allele Type: QTL
• Mutation: Undefined
• This allele confers decreased litter size compared to QSo.
• Inheritance: Recessive

Notes

Mapping and Phenotype information for this QTL, its variants and associated markers

J:44163

Highly prolific outbred (QSo) and inbred (IQ5) strains derived from the Quackenbush Swiss mouse line and the less prolific C57BL/6J inbred line were studied to identify quantitative trait loci (QTLs) for prolificacy growth. Analysis of F2 progeny suggested the presence of a QTL (Fecq2) associated with litter size on mouse Chromosome 4, at D4Mit37 (LOD = 5.02). Suggestive, but not significant, linkage of mature weight has been associated with this region as well.

References

• Original: J:44163 Kirkpatrick BW, et al., Identification of quantitative trait loci for prolificacy and growth in mice. Mamm Genome. 1998 Feb;9(2):97-102
• All: 1 reference(s)