Szs2^C57BL/6J
QTL Variant Detail

Summary

• QTL variant: Szs2^C57BL/6J
• Name: seizure susceptibility 2; C57BL/6J
• MGI ID: MGI:2155930
• QTL: Szs2 Location: unknown Genetic Position: Chr4, cM position of peak correlated region/allele: 43.34 cM
• QTL Note: genome coordinates based on the marker associated with the peak LOD score

Variant origin

• Strain of Specimen: C57BL/6J

Variant description

• Allele Type: QTL
• Mutation: Undefined
• This allele confers increased seizure susceptibility compared to DBA/2J.
• Inheritance: Not Specified

Notes

Szs2 is observed to interact with Szs1.

Mapping and Phenotype information for this QTL, its variants and associated markers

J:38888

In a population of F2 mice derived from B6D2F1 x B6D2F1 hybrids the quantitative trait locus seizure severity 2 Szs2 was mapped to mouse Chromosome 4 near D4Mit19. Authors indicated that Kasz4(Szs2) maps to the same location as Asp2 (45.1 cM)

References

• Original: J:38888 Ferraro TN, et al., Mapping murine loci for seizure response to kainic acid. Mamm Genome. 1997 Mar;8(3):200-8
• All: 1 reference(s)