Atoh1^tm1Hzo
Targeted Allele Detail

Summary

• Symbol: Atoh1^tm1Hzo
• Name: atonal bHLH transcription factor 1; targeted mutation 1, Huda Y Zoghbi
• MGI ID: MGI:2155984
• Synonyms: Atoh1^null, Math1-, Math1^m1
• Gene: Atoh1 Location: Chr6:64706109-64708229 bp, + strand Genetic Position: Chr6, 30.03 cM
• Alliance: Atoh1^tm1Hzo page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:44241
• Parent Cell Line: AB2.1 (ES Cell)
• Strain of Origin: 129S7/SvEvBrd-Hprt1^b-m2

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• A PGK-HPRT cassette replaced the entire coding region. (J:44241)

Expression

In Mice Carrying this Mutation:	108 assay results 2 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Atoh1 Mutation: 37 strains or lines available

References

• Original: J:44241 Ben-Arie N, et al., Math1 is essential for genesis of cerebellar granule neurons. Nature. 1997 Nov 13;390(6656):169-72
• All: 24 reference(s)