Eye1^DBA/2J
QTL Variant Detail

Summary

• QTL variant: Eye1^DBA/2J
• Name: eye weight 1; DBA/2J
• MGI ID: MGI:2156116
• QTL: Eye1 Location: Chr5:4929531-4929650 bp Genetic Position: Chr5, Syntenic

Variant origin

• Strain of Specimen: DBA/2J

Variant description

• Allele Type: QTL
• Mutation: Undefined
• This allele confers increased eye weight compared to C57BL/6J. (J:53890)
• Inheritance: Dominant

Notes

Mapping and Phenotype information for this QTL, its variants and associated markers

J:53890

Eye weight differs significantly between inbred strains C57BL/6J and DBA/2J. Eye weight was measured in the 26 strains in the BXD (C57BL/6J x DBA/2J) RI line and the variation was tightly correlated with mouse Chromosome 5 marker D5Mit346. Phenotypic analysis of F2 mice derived from (C57BL/6J x DBA/2J) mice verified the Chromosome 5 location of this QTL.

References

• Original: J:53890 Zhou G, et al., Eye1 and Eye2: gene loci that modulate eye size, lens weight, and retinal area in the mouse. Invest Ophthalmol Vis Sci. 1999 Apr;40(5):817-25
• All: 1 reference(s)