Spint2^{Gt(KST272)Byg}
Gene trapped Allele Detail

Summary

• Symbol: Spint2^{Gt(KST272)Byg}
• Name: serine protease inhibitor, Kunitz type 2; gene trap KST272, BayGenomics
• MGI ID: MGI:2156187
• Synonyms: HAI-2/beta-geo, Spint2^{Gt(pGT1.8TM)272Wcs}
• Gene: Spint2 Location: Chr7:28955748-28981337 bp, - strand Genetic Position: Chr7, 16.94 cM
• Alliance: Spint2^{Gt(KST272)Byg} page

Mutation origin

• Mutant Cell Line: KST272
• Germline Transmission: Earliest citation of germline transmission: J:70273
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: pGT1TMpf
• Gene trap vector pGT1TMpfs was inserted into the gene.
• Inheritance: Recessive
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  KST272	CC144713 ; (MGI Seq Detail)	5' RACE	Chr7:28980936-28981048 bp (-)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  31 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Disease models

Expression

In Mice Carrying this Mutation:	34 assay results
In Structures Affected by this Mutation:	4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Spint2 Mutation: 15 strains or lines available

References

• Original: J:70273 Mitchell KJ, et al., Functional analysis of secreted and transmembrane proteins critical to mouse development. Nat Genet. 2001 Jul;28(3):241-9
• All: 7 reference(s)