Epha4^{Gt(PST038)Byg}
Gene trapped Allele Detail

Summary

• Symbol: Epha4^{Gt(PST038)Byg}
• Name: Eph receptor A4; gene trap PST038, BayGenomics
• MGI ID: MGI:2156201
• Synonyms: Epha4^{Gt(pGT1TM)38Wcs}, Epha4^lacZ, Epha4^PLAP, EphA4-PLAP
• Gene: Epha4 Location: Chr1:77343822-77491725 bp, - strand Genetic Position: Chr1, 39.55 cM, cytoband C1-C5
• Alliance: Epha4^{Gt(PST038)Byg} page

Mutation origin

• Mutant Cell Line: PST038
• Germline Transmission: Earliest citation of germline transmission: J:67920
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: pGT1TMpf
• Mutation details: Gene trap vector pGT1TMpfs was inserted into the gene. The modified gene trap contains two markers, a beta-geo fusion and IRES-PLAP (placental alkaline phosphatase) sequences.
• Inheritance: Recessive
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  PST038	CC144853 ; (MGI Seq Detail)	5' RACE	Chr1:77403187-77403330 bp (-)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  52 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Expression

In Mice Carrying this Mutation:	5 assay results
In Structures Affected by this Mutation:	2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Epha4 Mutation: 67 strains or lines available

References

• Original: J:67920 Leighton PA, et al., Defining brain wiring patterns and mechanisms through gene trapping in mice. Nature. 2001 Mar 8;410(6825):174-9
• All: 21 reference(s)