Ptprf^Gt(ST534)Byg
Gene trapped Allele Detail

Summary

• Symbol: Ptprf^Gt(ST534)Byg
• Name: protein tyrosine phosphatase receptor type F; gene trap ST534, BayGenomics
• MGI ID: MGI:2156205
• Synonyms: LAR^-, Ptprf^{Gt(pGT1.8TM)534Wcs}
• Gene: Ptprf Location: Chr4:118065410-118148602 bp, - strand Genetic Position: Chr4, 54.47 cM, cytoband C6-D1
• Alliance: Ptprf^Gt(ST534)Byg page

Mutation origin

• Mutant Cell Line: ST534
• Germline Transmission: Earliest citation of germline transmission: J:108603
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Gene trapped (Null/knockout)
• Mutation: Insertion of gene trap vector Vector: pGT1.8TM
• Mutation details: A gene trap, pGT1.8TM, insertion disrupted the gene. No detectable mRNA or protein expression by immunoblot analysis was detected in homozygous mice (J:107124, unpublished data). (J:73878)
• Inheritance: Recessive
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  ST534	CC144761 ; (MGI Seq Detail)	5' RACE	Chr4:118106095-118126414 bp (-)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  126 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ptprf Mutation: 100 strains or lines available

References

• Original: J:37528 Skarnes WC, et al., Capturing genes encoding membrane and secreted proteins important for mouse development. Proc Natl Acad Sci U S A. 1995 Jul 3;92(14):6592-6
• All: 12 reference(s)