Szv1^C57BL/6J
QTL Variant Detail

Summary

• QTL variant: Szv1^C57BL/6J
• Name: seizure severity 1; C57BL/6J
• MGI ID: MGI:2156229
• QTL: Szv1 Location: unknown Genetic Position: Chr5, cM position of peak correlated region/allele: 26.02 cM
• QTL Note: genome coordinates based on the marker associated with the peak LOD score

Variant origin

• Strain of Specimen: C57BL/6J

Variant description

• Allele Type: QTL
• Mutation: Undefined
• This allele confers increased kainic acid induced seizure severity compared to DBA/2J. (J:38888)
• Inheritance: Recessive

Notes

Mapping and Phenotype information for this QTL, its variants and associated markers

J:38888

In a population of F2 mice derived from B6D2F1 x B6D2F1 hybrids the quantitative trait locus seizure severity 1 Szv1 was mapped to mouse Chromosome 5 near D5Mit11.

References

• Original: J:38888 Ferraro TN, et al., Mapping murine loci for seizure response to kainic acid. Mamm Genome. 1997 Mar;8(3):200-8
• All: 1 reference(s)