Summary |
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Variant origin |
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Variant description |
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Notes |
Sluc7 is observed to participate in additive interactions with other Sluc loci.
Mapping and Phenotype information for this QTL, its variants and associated markersJ:50525The fact that inbred O/20 was more susceptible to lung tumors then Congenic B10.O20 allowed for the mapping of lung tumor genes in OcB Recombinated Congenic strains. Lung tumor size and number could also be assesed by the QTL analysis of F2 mice derived from progenitor O/20 and various OcB strains. Analysis of F2 mice between O/20 and OcB-4 indicated a lung cancer susceptibility gene Sluc7 associated with mouse Chromosome 6 marker D6Mit158. |
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References |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 12/10/2024 MGI 6.24 |
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