Alcp12^C57BL/6J
QTL Variant Detail

Summary

• QTL variant: Alcp12^C57BL/6J
• Name: alcohol preference locus 12, male specific; C57BL/6J
• MGI ID: MGI:2156769
• QTL: Alcp12 Location: Chr7:128166122-128166379 bp Genetic Position: Chr7, cM position of peak correlated region/allele: 70.29 cM
• QTL Note: genome coordinates based on the marker associated with the peak LOD score

Variant origin

• Strain of Specimen: C57BL/6J

Variant description

• Allele Type: QTL
• Inheritance: Not Specified

Notes

Mapping and Phenotype information for this QTL, its variants and associated markers

J:52467

Alcohol consumption and preference in mice were analyzed as a QTL in Recombinant Inbreds(RI) AXB and BXA and progenitor inbreds C57BL/6J and A/J. In males QTLs were found on mouse Chromosomes 2, 5, 7, 10, 11 and 16, and in females QTLs were found on Chromosomes 2, 4, 5, 7, 11, 16, and 19. A QTL for alcohol preference in male AXB/BXA mice was associated with marker Tyr and D7Mit105 with a LOD score of 1.91 and 2.22 and designated as Alcp11 and Alcp12 respectively. In addition A QTL for alcohol preference in female AXB/BXA mice was also associated with marker Tyr with and is designated as Alcp13. An additional female QTL was associated with D7Mit105 with a LOD score of 1.84 and is designated as Alcp14.

References

• Original: J:52467 Gill K, et al., Alcohol preference in AXB/BXA recombinant inbred mice: gender differences and gender-specific quantitative trait loci. Mamm Genome. 1998 Dec;9(12):929-35
• All: 1 reference(s)