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Rigs1HLG
QTL Variant Detail
Summary
QTL variant: Rigs1HLG
Name: radiation induced gastroschisis 1; HLG
MGI ID: MGI:2156784
QTL: Rigs1  Location: Chr7:36280015-92394346 bp  Genetic Position: Chr7, cM position of peak correlated region/allele: 35.19 cM
QTL Note: genome coordinates based on the marker associated with the peak LOD score
Variant
origin
Strain of Specimen:  HLG
Variant
description
Allele Type:    QTL
Mutation:    Undefined
    This allele confers increased risk of radiation-induced gastroschisis compared to C57BL/6J. (J:52090)
Inheritance:    Recessive
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Notes

Mapping and Phenotype information for this QTL, its variants and associated markers

J:52090

The authors have mapped radiation induced gastroschisis (abdominal wall defect) QTL using genome wide microsatellite typing for markers in a group of mice with gastroschisis to mouse Chromosome 7. At least one of the loci responsible for this trait maps close to D7Mit195 (linkage p = 0.00082) encompassing the interval D7Mit227 and D7Mit148.

References
Original:  J:52090 Hillebrandt S, et al., A locus for radiation-induced gastroschisis on mouse Chromosome 7. Mamm Genome. 1998 Dec;9(12):995-7
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory