Pax6^9Neu
Chemically induced Allele Detail

Summary

• Symbol: Pax6^9Neu
• Name: paired box 6; 9, Neuherberg
• MGI ID: MGI:2156821
• Synonyms: nPMS-9
• Gene: Pax6 Location: Chr2:105499245-105527709 bp, + strand Genetic Position: Chr2, 55.31 cM
• Alliance: Pax6^9Neu page

Mutation origin

• Strain of Origin: (102 x C3H)F1

Mutation description

• Allele Type: Chemically induced (other)
• Mutation: Intragenic deletion
• Mutation details: The mutation, which was induced by treatment of a male mouse with n-propyl methanesulfonate (nPMS), was identified as 7 bp deletion in exon 5, nucleotide position 261-267. The resulting protein would contain the first 32 amino acids, 17 aberrant amino acids, followed by a stop codon. (J:73625)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Pax6 Mutation: 94 strains or lines available

Notes

Genbank Accession ID: AJ292077

References

• Original: J:63651 Favor J, et al., Saturation mutagenesis for dominant eye morphological defects in the mouse Mus musculus. Mamm Genome. 2000 Jul;11(7):520-5
• All: 3 reference(s)