Zic1^tm1Jaru
Targeted Allele Detail

Summary

• Symbol: Zic1^tm1Jaru
• Name: zinc finger protein of the cerebellum 1; targeted mutation 1, Jun Aruga
• MGI ID: MGI:2156822
• Gene: Zic1 Location: Chr9:91240111-91247863 bp, - strand Genetic Position: Chr9, 48.26 cM
• Alliance: Zic1^tm1Jaru page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:73794
• Parent Cell Line: J1 (ES Cell)
• Strain of Origin: 129S4/SvJae

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A targeting vector containing a neo cassette replaced the first exon containing the start codon and encoding three of the five zinc fingers. (J:73794)

Disease models

Expression

In Mice Carrying this Mutation:	33 assay results
In Structures Affected by this Mutation:	4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Zic1 Mutation: 32 strains or lines available

References

• Original: J:73794 Aruga J, et al., Mouse Zic1 is involved in cerebellar development. J Neurosci. 1998 Jan 1;18(1):284-93
• All: 10 reference(s)