Zfp110^tm1Mpin
Targeted Allele Detail

Summary

• Symbol: Zfp110^tm1Mpin
• Name: zinc finger protein 110; targeted mutation 1, Max-Planck-Institute for Neurobiology
• MGI ID: MGI:2156881
• Synonyms: nrif -
• Gene: Zfp110 Location: Chr7:12568688-12584504 bp, + strand Genetic Position: Chr7, 7.66 cM
• Alliance: Zfp110^tm1Mpin page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:66924
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The region encoding the p75 binding domain was replaced with a neo cassette. The absence of transcript from the targeted region was confirmed by RT-PCR. (J:66924)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Zfp110 Mutation: 32 strains or lines available

References

• Original: J:66924 Casademunt E, et al., The zinc finger protein NRIF interacts with the neurotrophin receptor p75(NTR) and participates in programmed cell death. EMBO J. 1999 Nov 1;18(21):6050-61
• All: 3 reference(s)