Rasgrf1^tm1Toc
Targeted Allele Detail

Summary

• Symbol: Rasgrf1^tm1Toc
• Name: RAS protein-specific guanine nucleotide-releasing factor 1; targeted mutation 1, Bruno Tocque
• MGI ID: MGI:2157017
• Synonyms: Grf-1 -
• Gene: Rasgrf1 Location: Chr9:89791961-89909030 bp, + strand Genetic Position: Chr9, 47.31 cM
• Alliance: Rasgrf1^tm1Toc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:47681
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: The gene was disrupted by deletion of an exon coding for the catalytic domain present in all isoforms of the encoded protein. (J:47681)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rasgrf1 Mutation: 66 strains or lines available

References

• Original: J:47681 Itier JM, et al., Imprinted gene in postnatal growth role [letter]. Nature. 1998 May 14;393(6681):125-6
• All: 2 reference(s)