Agtr1b^tm1Ii
Targeted Allele Detail

Summary

• Symbol: Agtr1b^tm1Ii
• Name: angiotensin II receptor, type 1b; targeted mutation 1, Iekuni Ichikawa
• MGI ID: MGI:2157019
• Gene: Agtr1b Location: Chr3:20368637-20421341 bp, - strand Genetic Position: Chr3, 6.37 cM
• Alliance: Agtr1b^tm1Ii page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:39712
• Parent Cell Line: E14.1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: An in-frame lacZ gene followed by a neomycin selection cassette was inserted into exon 3. Northern blot analysis demonstrated that the encoded transcript was not detectable in adreanal glands of homozygous mice. (J:39712)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Agtr1b Mutation: 18 strains or lines available

References

• Original: J:39712 Chen X, et al., Targeting deletion of angiotensin type 1B receptor gene in the mouse. Am J Physiol. 1997 Mar;272(3 Pt 2):F299-304
• All: 8 reference(s)