Daq19^CAST/Ei
QTL Variant Detail

Summary

• QTL variant: Daq19^CAST/Ei
• Name: directional asymmetry QTL 19; CAST/Ei
• MGI ID: MGI:2157023
• QTL: Daq19 Location: Chr8:32506572-32506729 bp Genetic Position: Chr8, cM position of peak correlated region/allele: 18.89 cM
• QTL Note: genome coordinates based on the marker associated with the peak LOD score

Variant origin

• Strain of Specimen: CAST/Ei

Variant description

• Allele Type: QTL
• Mutation: Undefined
• No mention of Jax in original reference. Earliest JR00928 ref 1993. mnk 03092018
• Inheritance: Not Specified

Notes

Mapping and Phenotype information for this QTL, its variants and associated markers

J:64141

92 microsatellite markers were typed in 350 M16i x (M16i x CAST/Ei)F1 backcross animals to identify QTLs affecting directional asymmetry (DA) and fluctuating asymmetry (FA) of the mandible in 12 week old animals. M16i is an inbred line selectively bred for rapid growth rate and CAST/Ei is a wild-derived inbred strain. 3 significant QTLs for mandible DA mapped to mouse Chromosome 2 from 25 cM - 43 cM (Daq17, LOD = 5.62 near D2Mit61) and 65 cM - 72 cM (Daq18, LOD>3.25 near D2Mit224) and mouse Chromosome 8 from 14 cM - 23 cM (Daq19, LOD = 3.67 at D8Mit4). Daq17, Daq18, and Daq19 were also associated with mandible size. Putative QTLs affecting mandible DA mapped to Chromosome 7 from 21 cM - 91 cM (LOD = 2.38 near D7Mit55), Chromosome 10 from 22 cM - 49 cM (LOD = 3.18 near D10Mit31), Chromosome 11 from 10 cM - 53 cM (LOD = 2.17 near D11Mit63), Chromosome 14 from 40 cM - 48 cM (LOD = 2.19 at D14Mit42), and Chromosome 17 from 19 cM - 31 cM (LOD = 2.17 at D17Mit22). No QTLs were identified for mandible FA.

References

• Original: J:64141 Leamy LJ, et al., Quantitative trait loci for directional but not fluctuating asymmetry of mandible characters in mice. Genet Res. 2000 Aug;76(1):27-40
• All: 1 reference(s)