Scc8^STS/A
QTL Variant Detail

Summary

• QTL variant: Scc8^STS/A
• Name: colon tumor susceptibility 8; STS/A
• MGI ID: MGI:2157035
• QTL: Scc8 Location: Chr8:7212499-35110107 bp Genetic Position: Chr8, cM position of peak correlated region/allele: 5.91 cM
• QTL Note: genome coordinates based on the marker associated with the peak LOD score

Variant origin

• Strain of Specimen: STS/A

Variant description

• Allele Type: QTL
• Mutation: Undefined
• This allele confers susceptibility to colon tumors compared to BALB/cHeA. (J:57235)
• Inheritance: Other (see notes)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Notes

Scc8 participates in interactive effects with Scc7. STS/A-derived alleles at Scc7 and Scc8 confers susceptibility to colon tumors.

References

• Original: J:57235 van Wezel T, et al., Four new colon cancer susceptibility loci, Scc6 to Scc9 in the mouse. Cancer Res. 1999 Sep 1;59(17):4216-8
• All: 1 reference(s)