Siafq1^DBA/2
QTL Variant Detail

Summary

• QTL variant: Siafq1^DBA/2
• Name: stress induced analgesia, female specific, QTL1; DBA/2
• MGI ID: MGI:2157074
• QTL: Siafq1 Location: unknown Genetic Position: Chr8, Syntenic

Variant origin

• Strain of Specimen: DBA/2

Variant description

• Allele Type: QTL
• Mutation: Undefined
• This allele confers increased stress-induced analgesia (SIA) compared to C57BL/6. (J:43467)
• Inheritance: Not Specified

Notes

Mapping and Phenotype information for this QTL, its variants and associated markers

J:43467

Analysis of BXD RI strains and (C57BL/6 x DBA/2)F2 mice indicated that the quantitative trait locus Siafq1 was statistically associated with D8Rik78 in the distal portion of mouse Chromosome 8. Authors did not identify any candidate genes relative to theSiafq1 phenotype in the associated region of mouse Chromosome 8. The significant association of the Siafq1 with D8Rik78 was observed in female mice only.

References

• Original: J:43467 Mogil JS, et al., Identification of a sex-specific quantitative trait locus mediating nonopioid stress-induced analgesia in female mice. J Neurosci. 1997 Oct 15;17(20):7995-8002
• All: 1 reference(s)