Rapop4^C3H/Kam
QTL Variant Detail

Summary

• QTL variant: Rapop4^C3H/Kam
• Name: radiation-induced apoptosis 4; C3H/Kam
• MGI ID: MGI:2157486
• QTL: Rapop4 Location: unknown Genetic Position: Chr11, Syntenic

Variant origin

• Strain of Specimen: C3H/Kam

Variant description

• Allele Type: QTL
• Mutation: Undefined
• This allele confers increased radiation-induced apoptosis in thymocytes compared to C57BL/6J. (J:44257)
• Inheritance: Other (see notes)

Notes

Rapop4 exhibits additive inheritance.

Mapping and Phenotype information for this QTL, its variants and associated markers

J:44257

In a genome wide scan a quantitative trait locus (QTL), Rapop4, controlling radiation induced thymocyte apoptosis in (C57BL/6J x C3Hf/Kam)F2 mice was associated with loci on mouse Chromosome 11. A maximum LRS (likelihood ratio statistic) of 19.9 was calculated to show a significant association of Rapop4 with D11Mit35.

References

• Original: J:44257 Weil MM, et al., Identification of quantitative trait loci controlling levels of radiation-induced thymocyte apoptosis in mice. Genomics. 1997 Nov 1;45(3):626-8
• All: 1 reference(s)