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Eae18NOD
QTL Variant Detail
Summary
QTL variant: Eae18NOD
Name: experimental allergic encephalomyelitis susceptibility 18; NOD
MGI ID: MGI:2157550
QTL: Eae18  Location: Chr18:57590559-82604728 bp  Genetic Position: Chr18, Syntenic
Variant
origin
Strain of Specimen:  NOD
Variant
description
Allele Type:    QTL
Mutation:    Undefined
    This allele confers EAE resistance compared to ABH. (J:29171)
Inheritance:    Recessive
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Notes

Mapping and Phenotype information for this QTL, its variants and associated markers

J:29171

The segregation of genes that may contribute to the susceptibility of experimental allergic encephalomyelitis in mice was analyzed in (ABH x NOD)F1 x NOD backcross mice. In a genome wide scan including all autosomes and the X-Chromosome a total of 100 microsatellites were examined.

Significant association of Eae18 with mouse Chromosome 18 was indicated and included a region defined by the proximal locus D18Mit19 and the distal locus D18Nds1.

References
Original:  J:29171 Baker D, et al., Genetic analysis of experimental allergic encephalomyelitis in mice. J Immunol. 1995 Oct 15;155(8):4046-51
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/22/2024
MGI 6.24
The Jackson Laboratory