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Dob3SWR/J
QTL Variant Detail
Summary
QTL variant: Dob3SWR/J
Name: dietary obesity 3; SWR/J
MGI ID: MGI:2157554
QTL: Dob3  Location: unknown  Genetic Position: Chr15, cM position of peak correlated region/allele: 15.74 cM
QTL Note: genome coordinates based on the marker associated with the peak LOD score
Variant
origin
Strain of Specimen:  SWR/J
Variant
description
Allele Type:    QTL
Mutation:    Undefined
    This allele confers decreased adiposity compared to AKR/J.
Inheritance:    Not Specified
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Notes

Mapping and Phenotype information for this QTL, its variants and associated markers

J:20700

Analysis of 189 (AKR x SWR/J) F2 mice indicates that a QTL (Dob3) affecting dietary obesity in AKR/J is located on Chromosome 15 between D15Nds2 and D15Mit22 with a peak LOD score of 3.93. The 189 animals used for statistical analysis represent the 10%tails of the phenotype distribution for the total F2 population (931 animals) and may not accurately represent the percentage of variance controlled by this locus. F1 X SWR/J backcross analysis confirmed the F2 mapping.

References
Original:  J:20700 West DB, et al., Dietary obesity linked to genetic loci on chromosomes 9 and 15 in a polygenic mouse model. J Clin Invest. 1994 Oct;94(4):1410-6
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory